TY - CHAP M1 - Book, Section TI - Dyslipidemia A1 - Talbert, Robert L. A2 - DiPiro, Joseph T. A2 - Talbert, Robert L. A2 - Yee, Gary C. A2 - Matzke, Gary R. A2 - Wells, Barbara G. A2 - Posey, L. Michael PY - 2017 T2 - Pharmacotherapy: A Pathophysiologic Approach, 10e AB - Content UpdateFebruary 1, 2019New Cholesterol Management Guidelines Emphasize Practicality and Clinical Judgment: The 2018 AHA/ACC Guideline on the Management of Blood Cholesterol reinforces the need to encourage lifestyle modification to prevent atherosclerotic cardiovascular disease (ASCVD) and to use high-potency statins in patients at high risk of major adverse cardiovascular (CV) events. LDL-C targets have been re-introduced into the guidelines. Combination therapy using a statin plus either ezetimibe or a PCSK-9 inhibitor should be considered in very high-risk patients who do not reach their LDL-C target. Clinicians and patients can now consider a wider array of risk-enhancing factors when making treatment decisions. Most patients no longer need to fast before obtaining a lipid profile. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1161376351 ER -