TY  - CHAP
M1  - Book, Section
TI  - Sickle Cell Disease
A1  - Wells, Barbara G.
A1  - DiPiro, Joseph T.
A1  - Schwinghammer, Terry L.
A1  - DiPiro, Cecily V.
PY  - 2017
T2  - Pharmacotherapy Quick Guide
AB  - Sickle  cell  syndromes,  which  can  be  divided  into  sickle  cell  trait  (SCT)  and  sickle  cell  disease  (SCD),  are  hereditary  conditions  characterized  by  the  presence  of  sickle  hemoglobin  (HbS)  in  red  blood  cells  (RBCs).SCT  is  the  heterozygous  inheritance  of  one  normal  β-globin  gene  producing  hemoglobin  A  (HbA)  and  one  sickle  gene  producing  HbS  (HbAS)  gene.  Individuals  with  SCT  are  asymptomatic.SCD  can  be  of  homozygous  or  compounded  heterozygous  inheritance.  Homozygous  HbS  (HbSS)  has  historically  been  referred  to  as  sickle  cell  anemia  (SCA).  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/25
UR  - accesspharmacy.mhmedical.com/content.aspx?aid=1144734839
ER  -