TY - CHAP M1 - Book, Section TI - Human Papillomavirus Infections A1 - Brown, Darron R. A1 - Ermel, Aaron A2 - Jameson, J. Larry A2 - Fauci, Anthony S. A2 - Kasper, Dennis L. A2 - Hauser, Stephen L. A2 - Longo, Dan L. A2 - Loscalzo, Joseph PY - 2018 T2 - Harrison's Principles of Internal Medicine, 20e AB - Interest in human papillomavirus (HPV) infection began in earnest in the 1980s after Harold zur Hausen postulated that infection with these viruses was associated with cervical cancer. It is now recognized that HPV infection of the human genital tract is extremely common and causes clinical conditions ranging from asymptomatic infection to genital warts (condylomata acuminata); dysplastic lesions and invasive cancers of the anus, penis, vulva, vagina, and cervix; and a subset of oropharyngeal cancers. This chapter describes the epidemiology of HPV as a virus and a pathogen, the natural history of HPV infections and associated cancers, strategies to prevent infection and HPV-associated disease, and treatment modalities for some conditions caused by HPV. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/16 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1159154909 ER -