TY - CHAP M1 - Book, Section TI - Sjögren’s Syndrome A1 - Moutsopoulos, Haralampos M. A2 - Jameson, J. Larry A2 - Fauci, Anthony S. A2 - Kasper, Dennis L. A2 - Hauser, Stephen L. A2 - Longo, Dan L. A2 - Loscalzo, Joseph PY - 2018 T2 - Harrison's Principles of Internal Medicine, 20e AB - Sjögren’s syndrome is a chronic, slowly progressing autoimmune disease characterized by lymphocytic infiltration of the exocrine glands resulting in xerostomia and dry eyes (keratoconjunctivitis sicca). The syndrome has unique features since it presents with a wide clinical spectrum from organ-specific autoimmune exocrinopathy to systemic disease. A small but significant number of patients develop malignant lymphoma. The disease can present as an entity alone or in association with other autoimmune diseases (Table 354-1). Finally, the histopathologic lesion in the labial minor salivary glands is easily accessible aiding the diagnosis, prognosis and disease pathogenesis. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1156606666 ER -