TY  - CHAP
M1  - Book, Section
TI  - Chronic Obstructive Pulmonary Disease
A1  - Andrus, Miranda R.
A1  - Pinner, Nathan A.
A2  - Sutton, S. Scott
PY  - 2019
T2  - McGraw-Hill's NAPLEX® Review Guide, 3e
AB  - Chronic  obstructive  pulmonary  disease  (COPD)  is  a  preventable  chronic  disease  of  the  airways  characterized  by  gradual,  progressive  loss  of  lung  function.  COPD  patients  have  airflow  limitation  that  is  not  fully  reversible.  The  airflow  limitation  is  associated  with  an  abnormal  inflammatory  response  of  the  lung  to  noxious  particles  or  gases.  Emphysema  and  chronic  bronchitis  are  often  present  in  COPD,  but  patients  must  also  have  abnormal  spirometry  to  be  formally  diagnosed  with  COPD.  Emphysema  is  an  abnormal  permanent  enlargement  of  the  airspaces  distal  to  the  terminal  bronchioles,  accompanied  by  destruction  of  their  walls  and  without  fibrosis.  Chronic  bronchitis  is  inflammation  of  the  bronchioles  with  mucus  hypersecretion  and  chronic  productive  cough.  Because  most  patients  exhibit  some  features  of  emphysema  and  chronic  bronchitis,  the  appropriate  emphasis  of  COPD  pathophysiology  is  on  small  airway  disease  and  parenchymal  damage  that  contributes  to  chronic  airflow  limitation.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/16
UR  - accesspharmacy.mhmedical.com/content.aspx?aid=1158315655
ER  -