TY - CHAP M1 - Book, Section TI - Osteoporosis A1 - Clements, Jennifer N. A2 - Sutton, S. Scott PY - 2019 T2 - McGraw-Hill's NAPLEX® Review Guide, 3e AB - Osteoporosis is a reduction in bone mineral density (BMD), loss of bone strength, and deterioration of the skeletal microarchitecture resulting in fragile bones. Due to a decrease in bone strength and loss of bone quality, there is an increased risk of fractures, particularly of the hip, spine, and wrist. Women have a higher risk of an osteoporotic fracture per year, compared to men; however, men have a higher mortality associated with an osteoporotic fracture. There are two types of bone in the human skeleton—cortical and trabecular. Cortical bone, or compact bone, is a dense, strong bone and forms the outer shell found in long and flat bones. Cortical bone accounts for bone strength and is 80% of the weight for the human skeleton. Trabecular bone, also known as cancellous bone, is porous (ie, sponge-like). This type of bone is soft, weak, and flexible and, therefore, susceptible to fracture. Trabecular bone is on interior surfaces of long bones, vertebrae, and distal forearms. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1158315819 ER -