TY - CHAP M1 - Book, Section TI - Clinical Use of Antimicrobial Agents A1 - Lampiris, Harry W. A1 - Maddix, Daniel S. A2 - Katzung, Bertram G. A2 - Vanderah, Todd W. PY - 2021 T2 - Basic & Clinical Pharmacology, 15e AB - CASE STUDYA 65-year-old man undergoes percutaneous nephrostomy for acute nephrolithiasis and urosepsis while travelling in India*. He receives systemic antimicrobial therapy with ciprofloxacin for 7 days and completely recovers. Two weeks later he returns to the USA and presents to the emergency department with confusion, dysuria, and chills. Physical exam reveals a blood pressure of 90/50, pulse 120, temperature 38.5°C and respiratory rate 24. The patient is disoriented but the physical exam is otherwise unremarkable. Laboratory test shows WBC 24,000/mm3 and elevated serum lactate; urinalysis shows 300 WBC per high power field and 4+ bacteria. What possible organisms are likely to be responsible for the patient’s symptoms? What antibiotic(s) would you choose for initial therapy of this potentially life-threatening infection? SN - PB - McGraw-Hill CY - New York, NY Y2 - 2024/03/28 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1176470047 ER -