TY  - CHAP
M1  - Book, Section
TI  - Classification of Chronic Hepatitis
A1  - Dienstag, Jules L.
A2  - Jameson, J. Larry
A2  - Fauci, Anthony S.
A2  - Kasper, Dennis L.
A2  - Hauser, Stephen L.
A2  - Longo, Dan L.
A2  - Loscalzo, Joseph
PY  - 2018
T2  - Harrison's Principles of Internal Medicine, 20e
AB  - Common  to  all  forms  of  chronic  hepatitis  are  histopathologic  distinctions  based  on  localization  and  extent  of  liver  injury.  These  vary  from  the  milder  forms,  previously  labeled  chronic  persistent  hepatitis  and  chronic  lobular  hepatitis,  to  the  more  severe  form,  formerly  called  chronic  active  hepatitis.  When  first  defined,  these  designations  were  believed  to  have  prognostic  implications,  which  were  not  corroborated  by  subsequent  observations.  Categorization  of  chronic  hepatitis  based  primarily  on  histopathologic  features  has  been  replaced  by  a  more  informative  classification  based  on  a  combination  of  clinical,  serologic,  and  histologic  variables.  Classification  of  chronic  hepatitis  is  based  on  (1)  its  cause;  (2)  its  histologic  activity,  or  grade;  and  (3)  its  degree  of  progression  based  on  level  of  fibrosis,  or  stage.  Thus,  neither  clinical  features  alone  nor  histologic  features—requiring  liver  biopsy  or  noninvasive  markers  of  fibrosis—alone  are  sufficient  to  characterize  and  distinguish  among  the  several  categories  of  chronic  hepatitis.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/20
UR  - accesspharmacy.mhmedical.com/content.aspx?aid=1178426792
ER  -