TY - CHAP M1 - Book, Section TI - Cystic Fibrosis A1 - Bimpasis, Lisa (Lubsch) A2 - Sutton, S. Scott PY - 2020 T2 - McGraw Hill’s NAPLEX® Review Guide, 4e AB - Cystic fibrosis (CF) is a life-threatening genetic disease of the epithelial cells in the body, especially those lining the intestinal tract and lungs. Normally, epithelial cells transport chloride through the cystic fibrosis transmembrane regulator (CFTR) with sodium and water following the ion flux. CF is the loss of the function of the CFTR with defective movement of chloride and water in the body. Thus, the composition of fluid secreted by the pancreas, airways, and other organs is thick and leads to obstruction with malfunction. This malfunction eventually leads to widespread organ system disease (Table 47-1). SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1179735415 ER -