TY - CHAP M1 - Book, Section TI - Histamine, Serotonin, Drugs Used in Obesity, Ergot Alkaloids, & Other Drugs Used in Migraine A1 - Katzung, Bertram G. A1 - Kruidering-Hall, Marieke A1 - Tuan, Rupa Lalchandani A1 - Vanderah, Todd W. A1 - Trevor, Anthony J. PY - 2021 T2 - Katzung & Trevor's Pharmacology: Examination & Board Review, 13e AB - Autacoids are endogenous molecules that do not fall into traditional autonomic groups. They do not act on cholinoceptors or adrenoceptors but have powerful pharmacologic effects on smooth muscle and other tissues. Histamine and serotonin (5-hydroxytryptamine; 5-HT) are the most important amine autacoids. The drugs used in obesity do not have significant smooth muscle effects but have some properties in common with the histamine and serotonin groups. The ergot alkaloids are a heterogeneous group of drugs (not autacoids) that interact with serotonin receptors, dopamine receptors, and α receptors. They are included in this chapter because of their effects on serotonin receptors and on smooth muscle. Several drugs used only for migraine headache target the calcitonin gene-related peptide receptor. Other peptide and eicosanoid autacoids are discussed in Chapters 17 and 18. Nitric oxide is discussed in Chapter 19. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1180555951 ER -