TY  - CHAP
M1  - Book, Section
TI  - Introduction to CNS Pharmacology
A1  - Katzung, Bertram G.
A1  - Kruidering-Hall, Marieke
A1  - Tuan, Rupa Lalchandani
A1  - Vanderah, Todd W.
A1  - Trevor, Anthony J.
PY  - 2021
T2  - Katzung & Trevor's Pharmacology: Examination & Board Review, 13e
AB  - Drugs  that  act  on  the  central  nervous  system  (CNS)  are  the  most  commonly  prescribed  drugs  in  current  use.  Most  of  these  drugs  act  by  changing  ion  flow  through  transmembrane  channels  of  nerve  cells.  Transmitter  reuptake  transporters  constitute  a  second  class  of  drug  targets,  especially  for  antidepressant  agents.  Inhibition  of  acetylcholine  metabolism  is  the  major  action  of  the  drugs  currently  approved  for  use  in  Alzheimer  disease  and  γ-aminobutyric  acid  (GABA)  metabolism  is  inhibited  by  an  anticonvulsant  agent.  Finally,  a  few  drugs  appear  to  act  by  altering  the  function  of  neuroglia.  These  satellite  cells  have  been  shown  to  modulate  transmitter  synthesis  and  disposition  and  support  neurons  metabolically.  Microglia  have  also  been  shown  to  “prune”  neuronal  networks  in  the  normal  development  of  the  CNS  and  possibly  in  Alzheimer  disease  and  schizophrenia.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accesspharmacy.mhmedical.com/content.aspx?aid=1180556206
ER  -