TY  - CHAP
M1  - Book, Section
TI  - Pharmacogenetics, Drug Metabolism, Transporters, and Individualization of Drug Therapy
A1  - Raccor, Brianne
A1  - Adams, Michael L.
A2  - Ducharme, Murray P.
A2  - Shargel, Leon
PY  - 2022
T2  - Shargel and Yu's Applied Biopharmaceutics and Pharmacokinetics, 8e
AB  - Define  pharmacogenetics  and  pharmacogenomics.Define  genetic  polymorphism  and  explain  the  difference  between  genotype  and  phenotype.Explain  with  relevant  examples  how  genetic  variability  influences  drug  response,  pharmacokinetics,  and  dosing  regimen  design.Describe  the  relevance  of  CYP  enzymes  and  their  genetic  variability  to  pharmacokinetics  and  dosing.List  the  major  drug  transporters  and  describe  how  their  genetic  variability  can  impact  pharmacokinetics.Discuss  the  main  issues  in  applying  genomic  data  to  patient  care;  for  example,  clinical  interpretation  of  data  from  various  laboratories  and  accuracy  of  record  keeping  of  large  amounts  of  genomic  data.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/24
UR  - accesspharmacy.mhmedical.com/content.aspx?aid=1188770230
ER  -