TY - CHAP
M1 - Book, Section
TI - Chapter 7. Toxicokinetics
A1 - Shen, Danny D.
A2 - Klaassen, Curtis D.
A2 - Watkins, John B.
PY - 2010
T2 - Casarett & Doull's Essentials of Toxicology, 2e
AB - Toxicokinetics is the study of the modeling and mathematical description of the time course of disposition (absorption, distribution, biotransformation, and excretion) of xenobiotics in the whole organism.The apparent volume of distribution (Vd) is the space into which an amount of chemical is distributed in the body to result in a given plasma concentration.Clearance describes the rate of chemical elimination from the body in terms of volume of fluid containing chemical that is cleared per unit of time.The half-life of elimination (T1/2) is the time required for the blood or plasma chemical concentration to decrease by one-half.
SN -
PB - The McGraw-Hill Companies
CY - New York, NY
Y2 - 2023/01/29
UR - accesspharmacy.mhmedical.com/content.aspx?aid=6480784
ER -