TY  - CHAP
M1  - Book, Section
TI  - Chapter 49. Antiviral Chemotherapy & Prophylaxis
A1  - Trevor, Anthony J.
A1  - Katzung, Bertram G.
A1  - Kruidering-Hall, Marieke M.
A1  - Masters, Susan B.
PY  - 2013
T2  - Katzung & Trevor's Pharmacology: Examination & Board Review, 10e
AB  - As  obligate  intracellular  parasites,  the  replication  of  viruses  depends  on  synthetic  processes  of  the  host  cell.  Antiviral  drugs  can  exert  their  actions  at  several  stages  of  viral  replication  including  viral  entry,  nucleic  acid  synthesis,  late  protein  synthesis  and  processing,  and  in  the  final  stages  of  viral  packaging  and  virion  release  (Figure  49–1).  Most  of  the  drugs  active  against  herpes  viruses  (HSV)  and  many  agents  active  against  human  immunodeficiency  virus  (HIV)  are  antimetabolites,  structurally  similar  to  naturally  occurring  compounds.  The  selective  toxicity  of  antiviral  drugs  usually  depends  on  greater  susceptibility  of  viral  enzymes  to  their  inhibitory  actions  than  host  cell  enzymes.  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2024/04/20
UR  - accesspharmacy.mhmedical.com/content.aspx?aid=56984153
ER  -