TY - CHAP M1 - Book, Section TI - Food Toxicology A1 - Kotsonis, Frank N. A1 - Burdock, George A. PY - 2012 T2 - Casarett and Doull's Toxicology: The Basic Science of Poisons, 8e AB - Introduction to Food ToxicologyUniqueness of Food ToxicologyNature and Complexity of FoodImportance of the Gastrointestinal TractSafety Standards for Foods, Food Ingredients and ContaminantsThe FD&C Act Provides for a Practicable ApproachThe Application of Experience: Generally Recognized as SafeUse of TolerancesFood and Color AdditivesThe Importance of LabelingMethods Used to Evaluate the Safety of Foods, Ingredients, and ContaminantsSafety Evaluation of Direct Food and Color AdditivesExposure: The Estimated Daily IntakeAssignment of Concern Level and Required TestingSafety Determination of Indirect Food AdditivesSafety Requirements for GRAS SubstancesEstablishing Safe Conditions of Use for New Foods, Macroingredients and New TechnologiesTransgenic Plant (and New Plant Varieties) PolicyFood MacroingredientsNanotechnologyFunctional FoodsFiberDMGSafety Requirements for Dietary SupplementsAssessment of CarcinogensCarcinogenicity as a Special ProblemBiological Versus Statistical SignificanceCarcinogenic ContaminantsAdverse Reactions to Food or Food IngredientsFood AllergyChemistry of Food AllergensDemographics of Food Allergy and IntoleranceFood IdiosyncrasyLactose IntoleranceFavism (Glucose-6-phosphate dehydrogenase deficiency)Asian Flush SyndromeAnaphylactoid ReactionsFood-Drug InteractionsMetabolic Food ReactionsExcess Consumption of a Normally Nontoxic FoodImproperly Prepared FoodPre- and Postharvest ChangesToxic Substances in FoodHeavy MetalsLeadCadmiumMercuryHalogenated Hydrocarbons (Polychlorinated and Polybrominated Hydrocarbons)Polychlorinated HydrocarbonsPolybrominated HydrocarbonsNitrosmaines, Nitrosamides, and N-Nitroso SubstancesFood-borne Molds and MycotoxinsAflatoxinsTrichothecenesFumonisinsOchratoxin AEthyl CarbamateFluorideToxins in Fish, Shellfish, and TurtlesMarine ToxinsInnate Marine ToxinsMicrobiological Agents—Preformed Bacterial ToxinsClostridium botulinum, C butyricum, and C barattiClostridium perfringensBacillus cereusStaphylococcus aureusE coliBovine Spongiform EncephalopathySubstances Produced by Cooking or ProcessingHeterocyclic AminesAcrylamideFuranMiscellaneous Contaminants in FoodConclusion SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/16 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1100092292 ER -