TY - CHAP M1 - Book, Section TI - Otolaryngologic Principles A1 - Chiang, William K. A2 - Hoffman, Robert S. A2 - Howland, Mary Ann A2 - Lewin, Neal A. A2 - Nelson, Lewis S. A2 - Goldfrank, Lewis R. PY - 2015 T2 - Goldfrank's Toxicologic Emergencies, 10e AB - Many xenobiotics adversely affect the senses of olfaction, gustation, and cochlear-vestibular functions. These toxic effects are not life-threatening but may pose significant distress to patients. Health care providers are often not familiar with the pathophysiology of these special senses. ­Furthermore, because of the lack of standardized diagnostic techniques and normal parameters, such adverse effects may be overlooked and dismissed by health care providers, despite significant patient distress and dysfunction. This is particularly true for disorders of olfaction and gustation. This chapter reviews the anatomy and physiology of these senses, describes the effects of xenobiotics on these senses, and examines the significant diagnostic information these senses contribute to identifying the presence of xenobiotics. Understanding the effects of xenobiotics on these senses may allow for early detection, removal, appropriate referral, treatment, and prevention of future events. In occupational settings, understanding these principles may prevent permanent and life-threatening injuries. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1108426622 ER -