TY - CHAP M1 - Book, Section TI - Congenital Heart Disease in the Adult A1 - Aboulhosn, Jamil A. A1 - Child, John S. A2 - Kasper, Dennis A2 - Fauci, Anthony A2 - Hauser, Stephen A2 - Longo, Dan A2 - Jameson, J. Larry A2 - Loscalzo, Joseph PY - 2014 T2 - Harrison's Principles of Internal Medicine, 19e AB - Over a hundred years ago, Sir William Osler, in his classic textbook The Principles and Practice of Medicine (New York, Appleton & Co, 1892, pp 659–663), devoted only five pages to “Congenital Affections of the Heart,” with the first sentence declaring that “[t]hese [disorders] have only limited clinical interest, as in a large proportion of cases the anomaly is not compatible with life, and in others nothing can be done to remedy the defect or even to relieve symptoms.” Fortunately, in the intervening century, considerable progress has been made in understanding the basis for these disorders and their effective treatment. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2022/05/24 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1120805595 ER -