TY - CHAP M1 - Book, Section TI - IgG4-Related Disease A1 - Stone, John H. A2 - Kasper, Dennis A2 - Fauci, Anthony A2 - Hauser, Stephen A2 - Longo, Dan A2 - Jameson, J. Larry A2 - Loscalzo, Joseph PY - 2014 T2 - Harrison's Principles of Internal Medicine, 19e AB - IgG4-related disease (IgG4-RD) is a fibroinflammatory condition characterized by a tendency to form tumefactive lesions. The clinical manifestations of this disease, however, are protean, and continue to be defined. IgG4-RD has now been described in virtually every organ system. Commonly affected organs are the biliary tree, salivary glands, periorbital tissues, kidneys, lungs, lymph nodes, and retroperitoneum. In addition, IgG4-RD involvement of the meninges, aorta, prostate, thyroid, pericardium, skin, and other organs is well described. The disease is believed to affect the brain parenchyma, the joints, the bone marrow, and the bowel mucosa only rarely (if ever). SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2021/04/11 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1120814000 ER -