TY  - CHAP
M1  - Book, Section
TI  - Quinidine
A1  - GONZALEZ, EDGAR R.
A1  - GONZALEZ, REBECCA B.
A2  - Cohen, Henry
PY  - 2015
T2  - Casebook in Clinical Pharmacokinetics and Drug Dosing
AB  - The  medicinal  effects  of  the  bark  of  the  cinchona  tree  have  been  known  for  over  350  years.  The  tree  is  indigenous  to  South  America  and  is  known  as  Peruvian,  Jesuit's,  or  Cardinal  Bark.  During  the  1600s  and  1700s,  Jesuit  priests  imported  cinchona  bark  from  South  America  to  Europe  where  it  was  used  as  a  powder,  extract,  or  infusion  to  treat  fevers  as  well  as  “rebellious  palpitation.”1,2  In  the  early  1800s,  Pelletier  and  Caventou  worked  to  isolate  the  more  than  20  structurally  related  alkaloids  found  in  the  bark  of  the  cinchona  tree,  quinine  and  quinidine  being  the  most  important  ones.1,  2,  and  3  Pelletier  and  Caventou  successfully  isolated  quinine  in  1820  (see  Figure  18-1).2,3  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accesspharmacy.mhmedical.com/content.aspx?aid=1112259255
ER  -