TY - CHAP M1 - Book, Section TI - Natural Products in Cancer Chemotherapy: Hormones and Related Agents A1 - Moy, Beverly A1 - Goss, Paul A1 - Lee, Richard J. A1 - Smith, Matthew A2 - Brunton, Laurence L. A2 - Chabner, Bruce A. A2 - Knollmann, Björn C. Y1 - 2015 N1 - T2 - Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 12e AB - The growth of a number of cancers is hormone dependent or regulated by hormones. Research in the fields of fertility, birth control, and menopause has yielded valuable hormone analogs and antagonists for the treatment of both breast and prostate cancer. These molecules interrupt the stimulatory axis created by systemic pools of androgens and estrogens, inhibit hormone production or binding to receptors, and ultimately block the complex expression of genes that promotes tumor growth and survival. These drugs have proven effective in extending survival and delaying or preventing tumor recurrence in breast cancer and prostate cancer. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2023/02/09 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1127871809 ER -