TY - CHAP M1 - Book, Section TI - Chronic Obstructive Pulmonary Disease A1 - Bourdet, Sharya V. A1 - Williams, Dennis M. A2 - DiPiro, Joseph T. A2 - Talbert, Robert L. A2 - Yee, Gary C. A2 - Matzke, Gary R. A2 - Wells, Barbara G. A2 - Posey, L. Michael Y1 - 2017 N1 - T2 - Pharmacotherapy: A Pathophysiologic Approach, 10e AB - Content UpdateJuly 30, 2019Using C-Reactive Protein (CRP) Testing to Guide Antibiotic Use for COPD Exacerbations: Almost half of COPD patients experience one or more acute exacerbations of symptoms each year. Acute exacerbations are triggered by a variety of causes, including upper respiratory tract infections in 70% to 80% of cases. Most patients who present with acute worsening of COPD symptoms are treated with antibiotics, but antibiotic overuse contributes to antimicrobial resistance and increases the risk of adverse effects. Researchers in the United Kingdom used C-reactive protein (CRP) testing as a biomarker to assess acute COPD exacerbations and to guide antibiotic prescribing. The results suggest that using the results of point-of-care CRP tests could significantly reduce the number of antibiotics prescribed without adversely impacting COPD symptoms or hospitalization rates. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1164511201 ER -