TY - CHAP M1 - Book, Section TI - Immunopharmacology A1 - Lake, Douglas F. A1 - Briggs, Adrienne D. A2 - Katzung, Bertram G. Y1 - 2017 N1 - T2 - Basic & Clinical Pharmacology, 14e AB - CASE STUDYA 45-year-old man with high-risk acute myelogenous leukemia undergoes high-dose chemotherapy followed by an allogeneic stem cell transplant from an unrelated donor. He receives tacrolimus and low-dose methotrexate as prophylaxis for graft-vs-host disease. One month after blood count recovery, he develops a skin rash despite ongoing tacrolimus therapy. A skin biopsy confirms grade II acute graft-vs-host disease. How should this case be pharmacologically managed at this point? SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1148441949 ER -