TY - CHAP M1 - Book, Section TI - Mastocytosis A1 - Akin, Cem A1 - Boyce, Joshua A. A2 - Jameson, J. Larry A2 - Fauci, Anthony S. A2 - Kasper, Dennis L. A2 - Hauser, Stephen L. A2 - Longo, Dan L. A2 - Loscalzo, Joseph Y1 - 2018 N1 - T2 - Harrison's Principles of Internal Medicine, 20e AB - Mastocytosis is defined by accumulation of clonally expanded mast cells in tissues such as skin, bone marrow, liver, spleen, and gut. The mast cell expansion is generally recognized in skin and/or bone marrow. Mastocytosis occurs at any age and has a slight preponderance in males. Mastocytosis is a rare disorder and its exact prevalence is not known; however, it is estimated to occur in ~1 in 20,000 people. Familial occurrence is rare, and atopy is not increased compared to the general population. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/16 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1155952409 ER -