TY - CHAP M1 - Book, Section TI - Clostridium difficile Infection, Including Pseudomembranous Colitis A1 - Gerding, Dale N. A1 - Johnson, Stuart A2 - Jameson, J. Larry A2 - Fauci, Anthony S. A2 - Kasper, Dennis L. A2 - Hauser, Stephen L. A2 - Longo, Dan L. A2 - Loscalzo, Joseph Y1 - 2018 N1 - T2 - Harrison's Principles of Internal Medicine, 20e AB - Clostridium difficile infection (CDI) is a unique colonic disease that is acquired most commonly in association with antimicrobial use and the consequent disruption of the normal colonic microbiota. The most commonly diagnosed diarrheal illness acquired in the hospital, CDI results from the ingestion of spores of C. difficile that vegetate, multiply, and secrete toxins, causing diarrhea and, in the most severe cases, pseudomembranous colitis (PMC). SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1159153579 ER -