TY  - CHAP
M1  - Book, Section
TI  - RNA Synthesis, Processing, & Modification
A1  - Weil, P. Anthony
A2  - Rodwell, Victor W.
A2  - Bender, David A.
A2  - Botham, Kathleen M.
A2  - Kennelly, Peter J.
A2  - Weil, P. Anthony
Y1  - 2018
N1  - 
T2  - Harper's Illustrated Biochemistry, 31e
AB  - OBJECTIVESAfter  studying  this  chapter,  you  should  be  able  to:Describe  the  molecules  involved  and  the  mechanism  of  RNA  synthesis.Explain  how  eukaryotic  DNA-dependent  RNA  polymerases,  in  collaboration  with  an  array  of  specific  accessory  factors,  can  differentially  transcribe  genomic  DNA  to  produce  specific  messenger  RNA  (mRNA)  precursor  molecules.Describe  the  structure  of  eukaryotic  mRNA  precursors,  which  are  highly  modified  internally  and  at  both  termini.Appreciate  the  fact  that  the  majority  of  mammalian  mRNA-encoding  genes  are  interrupted  by  multiple  nonprotein  coding  sequences  termed  introns,  which  are  interspersed  between  protein  coding  regions  termed  exons.Explain  that  since  intron  RNA  does  not  encode  protein,  the  intronic  RNA  must  be  specifically  and  accurately  removed  in  order  to  generate  functional  mRNAs  from  the  mRNA  precursor  molecules  in  a  series  of  precise  molecular  events  termed  RNA  splicing.Explain  the  steps  and  molecules  that  catalyze  mRNA  splicing,  a  process  that  converts  the  end-modified  precursor  molecules  into  mRNAs  that  are  functional  for  translation.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/16
UR  - accesspharmacy.mhmedical.com/content.aspx?aid=1160190931
ER  -