TY - CHAP M1 - Book, Section TI - Membranes: Structure & Function A1 - Weil, P. Anthony A2 - Rodwell, Victor W. A2 - Bender, David A. A2 - Botham, Kathleen M. A2 - Kennelly, Peter J. A2 - Weil, P. Anthony Y1 - 2018 N1 - T2 - Harper's Illustrated Biochemistry, 31e AB - OBJECTIVESAfter studying this chapter, you should be able to:Know that biologic membranes are mainly composed of a lipid bilayer and associated proteins and glycoproteins. The major lipids are phospholipids, cholesterol, and glycosphingolipids.Appreciate that membranes are asymmetric, dynamic structures containing a mixture of integral and peripheral proteins.Describe the widely accepted fluid mosaic model of membrane structure.Understand the concepts of passive diffusion, facilitated diffusion, active transport, endocytosis, and exocytosis.Recognize that transporters, ion channels, the Na+ − K+-ATPase, receptors, and gap junctions are important participants in membrane function.Be aware that a variety of disorders result from abnormalities of membrane structure and function, including familial hypercholesterolemia, cystic fibrosis, hereditary spherocytosis, among others. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1160191528 ER -