TY - CHAP M1 - Book, Section TI - Primary and Metastatic Tumors of the Nervous System A1 - DeAngelis, Lisa M. A1 - Wen, Patrick Y. A2 - Jameson, J. Larry A2 - Fauci, Anthony S. A2 - Kasper, Dennis L. A2 - Hauser, Stephen L. A2 - Longo, Dan L. A2 - Loscalzo, Joseph Y1 - 2018 N1 - T2 - Harrison's Principles of Internal Medicine, 20e AB - Primary brain tumors are diagnosed in ~78,000 people each year in the United States. At least 25,000 are malignant, and most of these are gliomas. Meningiomas account for 35%, vestibular schwannomas 10%, and central nervous system (CNS) lymphomas ~2%. Brain metastases are three times more common than all primary brain tumors combined and are diagnosed in ~150,000 people each year. Metastases to the leptomeninges and epidural space of the spinal cord each occur in ~3–5% of patients with systemic cancer and are also a major cause of neurologic disability. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1156505564 ER -