TY - CHAP M1 - Book, Section TI - Sepsis Syndromes A1 - Sutton, S. Scott A1 - Bland, Christopher M. A1 - Quidley, April M. A1 - Dunn, Brianne L. A1 - Branan, Trisha N. A2 - Sutton, S. Scott Y1 - 2019 N1 - T2 - McGraw-Hill's NAPLEX® Review Guide, 3e AB - Sepsis is a continuum of physiologic stages characterized by infection, systemic inflammation, and hypoperfusion leading to tissue injury and organ failure (Table 26-1 for definitions to utilize for sepsis syndromes). Risk factors for sepsis include extremes of age, cancer, immunodeficiency, chronic organ failure, genetic factors (male and non-white ethnic origin in North America), patients with bacteremia, and genetic polymorphisms associated with immune regulation. Pulmonary, gastrointestinal, genitourinary, and bloodstream infections account for the majority of sepsis cases. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2022/05/26 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1158314557 ER -