TY - CHAP M1 - Book, Section TI - Basic Concepts of Endocrine Regulation A1 - Barrett, Kim E. A1 - Barman, Susan M. A1 - Brooks, Heddwen L. A1 - Yuan, Jason X.-J. Y1 - 2019 N1 - T2 - Ganong's Review of Medical Physiology, 26e AB - OBJECTIVESAfter studying this chapter, you should be able to:Describe hormones and their contribution to whole body homeostatic mechanisms.Understand the chemical nature of different classes of hormones and how this determines their mechanism of action on target cells. Contrast membrane bound and intracellular hormone receptors and understand the principles of desensitization, down-regulation, and inactivation.Define how hormones are synthesized and secreted by cells of endocrine glands, including how peptide hormones are cleaved from longer precursors.Understand the effects of plasma hormone binding proteins (thyroid and steroid hormones) on the availability of hormones to their sites of action, and on the mechanisms that regulate hormone secretion.Explain the principles of feedback control (negative and positive) of hormone secretion.Understand the principles governing disease states that result from over- or under-production of key hormones. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1159052593 ER -