TY - CHAP M1 - Book, Section TI - Principles and Techniques Applied to Enhance Elimination A1 - Goldfarb, David S. A1 - Ghannoum, Marc A2 - Nelson, Lewis S. A2 - Howland, Mary Ann A2 - Lewin, Neal A. A2 - Smith, Silas W. A2 - Goldfrank, Lewis R. A2 - Hoffman, Robert S. Y1 - 2019 N1 - T2 - Goldfrank's Toxicologic Emergencies, 11e AB - Enhancing the elimination of a xenobiotic from a poisoned patient is a logical step after initial stabilization of the airway, breathing, and circulation; supportive measures; and techniques to inhibit absorption. Table 6–1 lists methods that might be used to enhance elimination. In this chapter, hemodialysis, hemoperfusion, and hemofiltration are considered extracorporeal treatments (ECTRs) because xenobiotic removal occurs in a blood circuit outside the body. Extracorporeal treatments are used infrequently because most poisonings are not amenable to removal by these methods. In addition, because these elimination techniques have associated adverse effects, costs, and complications, the risk-to-benefit analysis suggests they are only indicated in a relatively small proportion of patients and situations. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1163007162 ER -