TY - CHAP M1 - Book, Section TI - Parvoviruses A1 - Riedel, Stefan A1 - Hobden, Jeffery A. A1 - Miller, Steve A1 - Morse, Stephen A. A1 - Mietzner, Timothy A. A1 - Detrick, Barbara A1 - Mitchell, Thomas G. A1 - Sakanari, Judy A. A1 - Hotez, Peter A1 - Mejia, Rojelio Y1 - 2019 N1 - T2 - Jawetz, Melnick, & Adelberg's Medical Microbiology, 28e AB - Parvoviruses are the smallest DNA animal viruses. Because of the limited coding capacity of their genome, viral replication is dependent on functions supplied by replicating host cells or by coinfecting helper viruses. Parvovirus B19 is pathogenic for humans and has a tropism for erythroid progenitor cells. It is the cause of erythema infectiosum (“Fifth disease”), a common childhood exanthem; a polyarthralgia–arthritis syndrome in normal adults; aplastic crisis in patients with hemolytic disorders; chronic anemia in immunocompromised individuals; and fetal death. The human bocaviruses have been detected in respiratory specimens from children with acute respiratory disease and in stool samples, but a role in disease is unproven. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1163282101 ER -