TY - CHAP M1 - Book, Section TI - Drug-Induced Ophthalmic Disorders A1 - Gosser, Rena A2 - DiPiro, Joseph T. A2 - Yee, Gary C. A2 - Posey, L. Michael A2 - Haines, Stuart T. A2 - Nolin, Thomas D. A2 - Ellingrod, Vicki Y1 - 2020 N1 - T2 - Pharmacotherapy: A Pathophysiologic Approach, 11e AB - KEY CONCEPTS The eye is highly susceptible to drug toxicity due to its extensive vasculature. When ophthalmic disorders occur, all medications and biologic agents, irrespective of route of administration, are potential causes. It is difficult to fully quantify the incidence of drug-induced ophthalmic disorders due to the variety of causative factors and side-effect reporting behaviors of clinicians. The most common drug-induced ophthalmic disorders include dry eye, cataract, intraoperative floppy iris syndrome, optic neuropathy, and retinopathy. The severity of drug-induced ophthalmic disorders varies and depends on dose, pharmacokinetics, genetic predisposition, age, extremes of body weight, and/or duration of exposure. Health professionals and patients should discuss potential drug-induced ophthalmic disorders to ensure awareness, prompt identification, management, and treatment. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1182453332 ER -