TY - CHAP M1 - Book, Section TI - Antiseizure Drugs A1 - Rogawski, Michael A. A2 - Katzung, Bertram G. A2 - Vanderah, Todd W. Y1 - 2021 N1 - T2 - Basic & Clinical Pharmacology, 15e AB - CASE STUDYA 23-year-old woman presents to the office for consultation regarding her antiseizure medications*. Seven years ago, this otherwise healthy young woman had a tonic-clonic seizure at home. She was rushed to the emergency department, at which time she was alert but complained of headache. A consulting neurologist placed her on levetiracetam, 500 mg bid. Four days later, electroencephalography (EEG) showed rare right temporal sharp waves. Magnetic resonance imaging (MRI) was normal. One year after this episode, a repeat EEG was unchanged, and levetiracetam was gradually increased to 1000 mg bid. The patient had no significant adverse effects from this dosage. At age 21, she had a second tonic-clonic seizure while in college; further discussion with her roommate at that time revealed a history of two recent episodes of 1–2 minutes of altered consciousness with lip smacking (focal impaired awareness seizure, formerly complex partial seizure). A repeat EEG showed occasional right temporal spikes. What is one possible strategy for controlling her present symptoms? SN - PB - McGraw-Hill CY - New York, NY Y2 - 2024/03/29 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1176972494 ER -