TY - CHAP M1 - Book, Section TI - Intra-Abdominal Infections A1 - Schwinghammer, Terry L. A1 - DiPiro, Joseph T. A1 - Ellingrod, Vicki L. A1 - DiPiro, Cecily V. Y1 - 2021 N1 - T2 - Pharmacotherapy Handbook, 11e AB - Intra-abdominal infections are those contained within the peritoneum or retroperitoneal space. Two general types of intra-abdominal infections are discussed throughout this chapter: peritonitis and abscess.Peritonitis is defined as the acute, inflammatory response of peritoneal lining to microorganisms, chemicals, irradiation, or foreign body injury. It may be classified as either primary, secondary, or tertiary. With primary peritonitis, an intra-abdominal focus of disease may not be evident. In secondary peritonitis, a focal disease process is evident within the abdomen. Tertiary peritonitis occurs in critically ill patients and is infection that persists or recurs at least 48 hours after apparently adequate management of primary or secondary peritonitis.An abscess is a purulent collection of fluid separated from surrounding tissue by a wall consisting of inflammatory cells and adjacent organs. It usually contains necrotic debris, bacteria, and inflammatory cells. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/03/29 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1178897323 ER -