TY  - CHAP
M1  - Book, Section
TI  - Skin and Soft-Tissue Infections
A1  - Schwinghammer, Terry L.
A1  - DiPiro, Joseph T.
A1  - Ellingrod, Vicki L.
A1  - DiPiro, Cecily V.
Y1  - 2021
N1  - 
T2  - Pharmacotherapy Handbook, 11e
AB  - Bacterial  infections  of  the  skin  can  be  classified  as  primary  or  secondary  (Table  48-1).  Primary  bacterial  infections  are  usually  caused  by  a  single  bacterial  species  and  involve  areas  of  generally  healthy  skin  (eg,  impetigo  and  erysipelas).  Secondary  infections  develop  in  areas  of  previously  damaged  skin  and  are  frequently  polymicrobic.The  conditions  that  may  predispose  a  patient  to  the  development  of  skin  and  soft-tissue  infections  (SSTIs)  include:  (1)  a  high  concentration  of  bacteria;  (2)  excessive  moisture  of  the  skin;  (3)  inadequate  blood  supply;  (4)  availability  of  bacterial  nutrients;  and  (5)  damage  to  the  corneal  layer,  allowing  for  bacterial  penetration.The  majority  of  SSTIs  are  caused  by  gram-positive  organisms  on  the  skin  surface.  Staphylococcus  aureus  and  Streptococcus  pyogenes  account  for  the  majority  of  SSTIs.  Other  common  nosocomial  pathogens  include  Pseudomonas  aeruginosa  (11%),  enterococci  (9%),  and  Escherichia  coli  (7%).  
SN  - 
PB  - McGraw Hill
CY  - New York, NY
Y2  - 2024/04/19
UR  - accesspharmacy.mhmedical.com/content.aspx?aid=1178897529
ER  -