TY - CHAP M1 - Book, Section TI - Antiarrhythmic Drugs A1 - Katzung, Bertram G. A1 - Kruidering-Hall, Marieke A1 - Tuan, Rupa Lalchandani A1 - Vanderah, Todd W. A1 - Trevor, Anthony J. Y1 - 2021 N1 - T2 - Katzung & Trevor's Pharmacology: Examination & Board Review, 13e AB - Cardiac arrhythmias are the most common cause of death in patients with a myocardial infarction or terminal heart failure. They increase in prevalence in the elderly and atrial fibrillation is particularly common in this group. Arrhythmias are also the most serious manifestation of digitalis toxicity and are often associated with anesthetic procedures, hyperthyroidism, and electrolyte disorders. The drugs used for arrhythmias fall into five major groups or classes, but most have very low therapeutic indices and when feasible, nondrug therapies (cardioversion, pacemakers, ablation, implanted defibrillators) are used. In addition, conditions associated with certain arrhythmias, especially increased risk of thromboembolism in atrial fibrillation, must be treated with appropriate drugs from other groups (eg, anticoagulants). SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/24 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1180555736 ER -