TY - CHAP M1 - Book, Section TI - Clinical Pharmacology of the Antihelminthic Drugs A1 - Katzung, Bertram G. A1 - Kruidering-Hall, Marieke A1 - Tuan, Rupa Lalchandani A1 - Vanderah, Todd W. A1 - Trevor, Anthony J. Y1 - 2021 N1 - T2 - Katzung & Trevor's Pharmacology: Examination & Board Review, 13e AB - Helminths (worms) are multicellular parasites; they infect very large numbers of humans and cause a broad range of diseases.Antihelminthic drugs have diverse chemical structures, mechanisms of action, and properties. Many act against specific parasites, and few are devoid of significant toxicity to host cells. In addition to the direct toxicity of the drugs, reactions to dead and dying parasites may cause serious toxicity in patients. In the text that follows, the drugs are divided into three groups on the basis of the type of helminth primarily affected (nematodes, trematodes, and cestodes). The drugs of choice and alternative agents for selected important helminthic infections are listed in Table 53–1. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/18 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1180558692 ER -