TY - CHAP M1 - Book, Section TI - Chapter 6B. Phase II Drug-Metabolizing Enzymes A1 - Murray, Michael A2 - Bertino, Joseph S. A2 - DeVane, C. Lindsay A2 - Fuhr, Uwe A2 - Kashuba, Angela D. A2 - Ma, Joseph D. Y1 - 2013 N1 - T2 - Pharmacogenomics: An Introduction and Clinical Perspective AB - To outline the major pathways of drug biotransformation mediated by phase II enzymes.To define the properties and multiplicity of genes that encode phase II biotransformation enzymes.To emphasize the extent of genetic variation in important genes that mediate phase II drug biotransformation.To provide established examples of pharmacogenetic variants in phase II drug-metabolizing enzymes that influence drug therapy.To evaluate the evidence for additional examples of pharmacogenetic variation in drug-metabolizing enzymes that influence therapeutic outcomes with drugs. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/18 UR - accesspharmacy.mhmedical.com/content.aspx?aid=56878198 ER -