TY  - CHAP
M1  - Book, Section
TI  - Chapter 43. Beta-Lactam Antibiotics & Other Cell Wall Synthesis Inhibitors
A1  - Trevor, Anthony J.
A1  - Katzung, Bertram G.
A1  - Kruidering-Hall, Marieke M.
A1  - Masters, Susan B.
Y1  - 2013
N1  - 
T2  - Katzung & Trevor's Pharmacology: Examination & Board Review, 10e
AB  - Penicillins  and  cephalosporins  are  the  major  antibiotics  that  inhibit  bacterial  cell  wall  synthesis.  They  are  called  beta-lactams  because  of  the  unusual  4-member  ring  that  is  common  to  all  their  members.  The  beta-lactams  include  some  of  the  most  effective,  widely  used,  and  well-tolerated  agents  available  for  the  treatment  of  microbial  infections.  Vancomycin,  fosfomycin,  and  bacitracin  also  inhibit  cell  wall  synthesis  but  are  not  nearly  as  important  as  the  beta-lactam  drugs.  The  selective  toxicity  of  the  drugs  discussed  in  this  chapter  is  mainly  due  to  specific  actions  on  the  synthesis  of  a  cellular  structure  that  is  unique  to  the  microorganism.  More  than  50  antibiotics  that  act  as  cell  wall  synthesis  inhibitors  are  currently  available,  with  individual  spectra  of  activity  that  afford  a  wide  range  of  clinical  applications.  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2024/04/19
UR  - accesspharmacy.mhmedical.com/content.aspx?aid=56983617
ER  -