TY - CHAP M1 - Book, Section TI - Toxic Responses of the Reproductive System A1 - Foster, Paul M.D. A1 - Gray, L. Earl Y1 - 2012 N1 - T2 - Casarett and Doull's Toxicology: The Basic Science of Poisons, 8e AB - IntroductionThe Reproductive CycleReproductive Development and Sexual DifferentiationGametogenesisNeonatal DevelopmentInfantile DevelopmentPubertal DevelopmentRodent Models of PubertySelected Examples of Chemicals That Alter the Onset of Pubertal Landmarks in Rats After Acute In Utero and/or Lactational ExposuresSelected Examples of Chemicals That Alter the Onset of Pubertal Landmarks in Rats After Peripubertal ExposuresSexual MaturityHypothalamic–Pituitary–Gonadal AxisOvarian FunctionOogenesisCase Study—BusulfanOvarian CyclePostovarian ProcessesOviductsUterusTesticular Structure and FunctionTargets for ToxicityTesticular Structure and SpermatogenesisPosttesticular ProcessesErection and EjaculationCase Studies for Effects on the Malem-DinitrobenzeneEthylene Glycol Monomethyl EtherMating Behavior in the RatCervixVaginaFertilizationImplantationPlacentaPregnancyParturitionLactationSenescenceEndocrine Disruption (Including Screening and Puberty)Known Effects of EDCs in Humans and AnimalsEffects of Drugs on Human Sexual DifferentiationEffects of Plant and Fungal Products in Animals and HumansEffects of Organochlorine Compounds in HumansOccupational ExposuresEnvironmental AndrogensEnvironmental AntiandrogensFungicidesLinuron (Herbicide)p,p′-DDE (Pesticide Metabolite)Phthalates (Plasticizers)Environmental EstrogensEDC Screening ProgramsIn Vivo Mammalian AssaysAlternative Screening AssaysTesting for Reproductive ToxicityScreens and Multigeneration StudiesTesting for Endocrine Disrupting ChemicalsDevelopmental Syndromes and Tailored TestingTest Design and Numbers of F1 AnimalsTesting PharmaceuticalsNewer Guidelines and ApproachesEvaluation of Toxicity to ReproductionConcordance of End PointsConsistency Across GenerationsGraded Effects SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1100089353 ER -