TY  - CHAP
M1  - Book, Section
TI  - Biochemical and Metabolic Principles
A1  - Kleinschmidt, Kurt C.
A1  - Delaney, Kathleen A.
A2  - Hoffman, Robert S.
A2  - Howland, Mary Ann
A2  - Lewin, Neal A.
A2  - Nelson, Lewis S.
A2  - Goldfrank, Lewis R.
Y1  - 2015
N1  - 
T2  - Goldfrank's Toxicologic Emergencies, 10e
AB  - Xenobiotics  are  compounds  that  are  foreign  to  a  living  system.  Toxic  xenobiotics  interfere  with  critical  metabolic  processes,  causing  structural  damage  to  cells  or  altering  their  cellular  genetic  material.  The  specific  biochemical  sites  of  actions  that  disrupt  metabolic  processes  are  well  characterized  for  many  xenobiotics  although  mechanisms  of  cellular  injury  are  not.  This  chapter  reviews  the  biochemical  principles  that  are  relevant  to  an  understanding  of  the  damaging  effects  of  toxic  xenobiotics  and  the  biotransformation  enzymes  and  their  clinical  implications.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/18
UR  - accesspharmacy.mhmedical.com/content.aspx?aid=1108424950
ER  -