TY - CHAP M1 - Book, Section TI - Sedative-Hypnotics A1 - Lee, David C. A2 - Hoffman, Robert S. A2 - Howland, Mary Ann A2 - Lewin, Neal A. A2 - Nelson, Lewis S. A2 - Goldfrank, Lewis R. Y1 - 2015 N1 - T2 - Goldfrank's Toxicologic Emergencies, 10e AB - Sedative-hypnotics are xenobiotics that limit excitability (sedation) and or induce drowsiness and sleep (hypnosis). Anxiolytics (formerly known as minor tranquilizers) are medications prescribed for their sedative-hypnotic properties. Mythology of ancient cultures is replete with stories of xenobiotics that cause sleep or unconsciousness (Chap. 1). Sedative-hypnotics overdoses were described in the medical literature soon after the commercial introduction of bromide preparations in 1853. Other commercial xenobiotics that subsequently were developed include chloral hydrate, paraldehyde, sulfonyl, and urethane. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1108432229 ER -