TY - CHAP M1 - Book, Section TI - Levetiracetam A1 - Bauer, Larry A. Y1 - 2015 N1 - T2 - Applied Clinical Pharmacokinetics, 3e AB - Levetiracetam is a pyrrolidine-based compound effective in the management of partial and tonic-clonic seizures, and it is administered as the S-enantiomer of a stereoisomer pair (Table 16-1).1,2,3, and 4 It is also useful for the treatment of myoclonic seizures in patients with juvenile myoclonic epilepsy. Levetiracetam does not exhibit antiseizure properties in all models used to screen antiepileptic drugs, and its exact mechanism of action is largely unknown. It does bind to a synaptic vesicle protein, SV2A, present in brain tissue, and this action is thought to be important to its therapeutic actions.5,6 SN - PB - McGraw-Hill Medical CY - New York, NY Y2 - 2024/03/28 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1106304110 ER -