TY - CHAP M1 - Book, Section TI - Carbamazepine A1 - COHEN, HENRY A2 - Cohen, Henry Y1 - 2015 N1 - T2 - Casebook in Clinical Pharmacokinetics and Drug Dosing AB - Carbamazepine was first indicated and marketed for trigeminal neuralgia and was later found to be an effective antiepileptic.1 Carbamazepine is a broad-spectrum antiepileptic drug (AED) and is indicated for partial seizures with complex symptomatology (psychomotor, temporal lobe), generalized tonic-clonic seizures (grand mal), and mixed seizure patterns.2,3 Extended-release carbamazepine is also indicated alone or in combination with other antipsychotic agents for acute manic or mixed episodes associated with bipolar 1 disorder either as treatment or prevention.4 Carbamazepine may be used as an adjunct for the symptomatic management of the acute phase of schizophrenia in patients who are refractory to antipsychotics.4 Carbamazepine has also been used for the management of restless leg syndrome, peripheral neuropathy, diabetic peripheral neuropathy, and posttraumatic stress disorders.3,4 SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1112257014 ER -