TY - CHAP M1 - Book, Section TI - Pharmacokinetic Considerations in Oncology A1 - CEACAREANU, ALICE C. A1 - WINTROB, ZACHARY A.P. A2 - Cohen, Henry Y1 - 2015 N1 - T2 - Casebook in Clinical Pharmacokinetics and Drug Dosing AB - The anthracycline age began over half century ago, when a soil sample harvested near the Castel del Monte in Italy revealed Streptomyces peucetius, a new bacterial strain producing a bright red pigment that was found to have good activity against murine tumors. A mutated strain of S. peucetius was found to produce a different red compound that was named Adriamycin, after the Adriatic Sea. Today, also known as doxorubicin (DOXO), this prototype compound remains one of the most prescribed antineoplastic agents. Currently, more than 2,000 known DOXO analogues provide invaluable clinical and research applicability. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1112260281 ER -