TY - CHAP M1 - Book, Section TI - Autonomic Nervous System Structure and Medications A1 - Pelletier-Dattu, Catherine E. Y1 - 2017 N1 - T2 - Lange Smart Charts: Pharmacology, 2e AB - Table Graphic Jump Location|Download (.pdf)|PrintAcetylcholinesteraseEnzyme responsible for the degradation of Ach.Adrenergic Neuronal BlockersMedications that prevent NE from exiting the nerve terminal.AnisocoriaUnequal pupils.Intrinsic Sympathomimetic Activity (ISA)Drugs with paradoxical partial β-agonist properties; clinical significance unknown.Lipid SolubilityAccounts for the CNS side effects of a drug.Malignant HypertensionSeverely elevated blood pressure associated with CNS, renal, or cardiac symptoms.Membrane Stabilizing Activity (MSA)Imparts a local anesthetic quality to β-blockers; may contribute to antiarrhythmic property.MiosisPupillary constriction.Myasthenia GravisAutoimmune disease characterized by increasing muscle weakness with use due to the presence of antibodies to the Ach receptor at the neuromuscular junction.MydriasisPupillary dilation.Nonselective α-Adrenergic BlockersMedications that block α1- and α2-adrenergic sites.Nonselective β-BlockersMedications that block β1- and β2-adrenergic sites.PheochromocytomaTumor of the adrenal gland that secretes catecholamines.Plasma BindingAccounts for the drug interactions.Postural (orthostatic) HypotensionA 20 mm Hg drop in systolic blood pressure or 10 mm Hg drop in diastolic blood pressure within 3 minutes of standing due to a defect in the blood pressure control system.Raynaud's DiseaseVascular disorder characterized by peripheral vasoconstriction.Selective α-Adrenergic BlockersMedications that block α1-adrenergic sites only.Selective β-Adrenergic BlockersMedications that block β1-adrenergic sites only.Sjögren's SyndromeSyndrome of dry mouth and dry eyes due to lymphocytic infiltration of the salivary and lacrimal glands; often observed in patients with autoimmune disorders including RA and SLE.Tourette's SyndromeSyndrome characterized by motor and verbal tics.XerostomiaDry mouth. SN - PB - McGraw-Hill Medical CY - New York, NY Y2 - 2024/03/28 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1114498385 ER -