TY - CHAP M1 - Book, Section TI - Drugs Affecting the Endocrine System A1 - Pelletier-Dattu, Catherine E. Y1 - 2017 N1 - T2 - Lange Smart Charts: Pharmacology, 2e AB - Table Graphic Jump Location|Download (.pdf)|PrintAcromegalySyndrome associated with excessive levels of growth hormone after puberty; symptoms include thickened skin, vocal hoarseness, joint pain, insulin resistance, hypertension, and cardiovascular disease.AstheniaDebility or weakness.Carcinoid SyndromeSymptoms associated with excessive levels of serotonin secreted by carcinoid tumors; symptoms include facial swelling, diarrhea, bronchial spasm, tachycardia, hypotension, and right-sided valvular disease.Central Precocious PubertyEarly onset of puberty due to activation of the gonadotropins leading to maturation of the gonads; this early gonadal maturation leads to early secretion of sex hormones and, therefore, early onset of secondary sexual characteristics in adolescents.CraniosynostosisPremature closure of the cranial sutures.Cushing's DiseaseDisease associated with excessive glucocorticoid levels most commonly caused by an adrenal cortical adenoma; symptoms include fat redistribution with a characteristic buffalo hump, thin extremities, hypertension, hirsutism, infertility, and amenorrhea.Diabetes InsipidisSyndrome due to insufficient levels of ADH (central) or decreased renal response to ADH (peripheral); symptoms resemble the excessive thirst and urination associated with diabetes mellitus.EndometriosisGrowth of cells of the uterine lining outside of the uterus; symptoms include pelvic pain and infertility.HyperprolactinemiaSyndrome associated with excessive levels of prolactin; symptoms include infertility, amenorrhea, galactorrhea, and mastodynia.Hypogonadotropic HypogonadismInadequate function of the gonads due to insufficient secretion of pituitary gonadotropins.Kaposi's SarcomaRare skin malignancy characterized by soft blue-black plaques and is typically seen in elderly and immunosuppressed patients; it is caused by human herpes virus 8.OligospermiaLow sperm count.SIADHSyndrome of inappropriate ADH; numerous causes include trauma, tumors, endocrine disorders, and drugs; excessive levels of ADH lead to hypernatremia.SteatorrheaLarge amounts of fat in the feces.Uterine FibroidsBenign smooth muscle tumors; their growth is related to estrogen.VirilizationAcquisition of adult male characteristics in women or prepubescent males. SN - PB - McGraw-Hill Medical CY - New York, NY Y2 - 2024/04/19 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1114498685 ER -