TY - CHAP M1 - Book, Section TI - Respiratory Physiology: Introduction A1 - Barrett, Kim E. A1 - Barman, Susan M. A1 - Boitano, Scott A1 - Brooks, Heddwen L. Y1 - 2018 N1 - T2 - Ganong’s Review of Medical Physiology, 25e AB - Respiration, or the uptake of O2 and removal of CO2 from the body as a whole, is the primary goal of the lung. At rest, a normal human breathes 12–15 times a minute. With each breath containing ~500 mL of air, this translates to 6–8 L of air that is inspired and expired every. Once the air reaches the depths of the lung in the alveoli, simple diffusion allows O2 to enter the blood in the pulmonary capillaries and CO2 to enter the alveoli, from where it can be expired. Using some basic math, on average, 250 mL of O2 enters the body per minute and 200 mL of CO2 is excreted. In addition to the O2 that enters the respiratory system, inspired air also contains a variety of particulates that must be properly filtered and/or removed to maintain lung health. Finally, although humans have a certain amount of control over breathing, most of the minute to minute function, including the fine adjustments necessary for proper lung function, are accomplished independent of voluntary control. The goal of this section is to review basic concepts that underlie important aspects of the control and outcome of breathing as well as to highlight other important functions in respiratory physiology. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1115832208 ER -