TY  - CHAP
M1  - Book, Section
TI  - Designing Patient Treatment Plans: Pharmacokinetic Foundations
A1  - Earle, Sandra B.
A2  - Nemire, Ruth E.
A2  - Kier, Karen L.
A2  - Assa-Eley, Michelle
Y1  - 2015
N1  - 
T2  - Pharmacy Student Survival Guide, 3e
AB  - Objectives:  Upon  completion  of  the  chapter  and  exercises,  the  student  pharmacist  will  be  able  toDefine  components  of  a  dosage  regimen  (dose  rate  and  dose  interval)  and  predict  how  they  influence  concentrations  of  drug  in  the  plasma.  (Css,avg  and  P:T).List  the  factors  influencing  the  bioavailability  of  an  orally  administered  drug.List  the  determinants  of  volume  of  distribution  and  why  volume  changes  may  or  may  not  matter.List  the  determinants  of  renal  clearance  and  determine  how  drugs  and  disease  may  alter  renal  clearance  and  thus  alter  Css,avg  and/or  P:T  of  a  given  drug  cleared  by  the  kidney.List  the  determinants  of  hepatic  clearance  and  determine  how  drugs  and  disease  may  alter  hepatic  clearance  and  thus  alter  Css,avg  and/or  P:T  of  a  given  drug  cleared  by  the  liver.Given  appropriate  concentration-time  data,  calculate  k,  t½,Cmax,  Cmin,  and  AUC  for  that  drug  in  that  patient.Explain  the  reasons  for  drug  monitoring  and  how  that  will  impact  the  patient's  outcome.Discuss  the  attributes  of  extended-interval  dosing  and  traditional  dosing  for  aminoglycosides.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/23
UR  - accesspharmacy.mhmedical.com/content.aspx?aid=1117502162
ER  -