TY  - CHAP
M1  - Book, Section
TI  - Multiple-Dosage Regimens
A1  - Siwale, Rodney C.
A1  - Sani, Shabnam N.
A2  - Shargel, Leon
A2  - Yu, Andrew B.C.
PY  - 2016
T2  - Applied Biopharmaceutics & Pharmacokinetics, 7e
AB  - Define  the  index  for  measuring  drug  accumulation.Define  drug  accumulation  and  drug  accumulation  t1/2.Explain  the  principle  of  superposition  and  its  assumptions  in  multiple-dose  regimens.Calculate  the  steady-state  Cmax  and  Cmin  after  multiple  IV  bolus  dosing  of  drugs.Calculate  k  and  VD  of  aminoglycosides  in  multiple-dose  regimens.Adjust  the  steady-state  Cmax  and  Cmin  in  the  event  the  last  dose  is  given  too  early,  too  late,  or  totally  missed  following  multiple  IV  dosing.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/20
UR  - accesspharmacy.mhmedical.com/content.aspx?aid=1117898190
ER  -